Matrixport Predicts “DeFi Renaissance” Fueled by Trump’s Return

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As a pro-crypto administration forms under Donald Trump, the U.S. could be poised for a revolution in decentralized finance (DeFi), according to an analysis by Matrixport.

Potential appointees for key positions at the U.S. Treasury, Department of Commerce, and SEC are seen as officials who could reshape financial policies and closely integrate the nation with the cryptocurrency sector.

Matrixport analysts suggest that the narrative of Bitcoin as “digital gold” might shift to a “DeFi renaissance.” This implies greater adoption of decentralized applications (dapps) or blockchain technology by traditional finance (TradFi) institutions to enhance the efficiency of payment systems and transactions.

“While the establishment of clear regulations may be anticipated, the ‘digitization’ of the U.S. financial economy could position crypto applications as the biggest ‘winners.’ This shift will push other governments to embrace digital assets, accelerating global adoption.”

The analysis also highlighted Bitcoin’s appeal amid macroeconomic uncertainty, particularly following comments by Treasury Secretary nominee Scott Bessent about reducing the budget deficit.

Experts at Matrixport view the creation of a strategic Bitcoin reserve as “increasingly likely.” They noted that even in the absence of active acquisitions, the U.S. government would “retain existing reserves indefinitely.”

Former CFTC Chairman and potential “crypto czar” Christopher Giancarlo previously called digital assets a priority for the Trump administration.

The Block recently reported a market shift in interest from meme coins to DeFi tokens.